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Tirosint®-SOL Brand Levothyroxine Oral Solution


Description:  Tirosint®-SOL is a brand-name levothyroxine which comes in a liquid form, packaged in an individual-dose ampule. 

Because it has no dyes, and few excipients, Tirosint®-SOL is considered an especially safe and effective option for people with allergies and sensitivities to dyes and excipients.  

Tirosint®-SOL is also shown in research to be more resistant than levothyroxine tablets to the negative effects of food, coffee, milk, soy foods, and a high-fiber diet. Tirosint®-SOL’s resistance also means that it’s a safe and effective option for the many hypothyroid patients who also take calcium supplements, iron supplements, proton pump inhibitor drugs, and antacids. 

Tirosint®-SOL has also been shown to be better absorbed by hypothyroid patients who have any issues with absorption, or specific gastrointestinal or digestive conditions that negatively affect levothyroxine tablet absorption. These conditions include:  


  • Celiac disease

  • Inflammatory bowel disease/syndrome (IBD/IBS)

  • Ulcers and helicobacter pylori (H. pylori) infection

  • Gastrointestinal reflux disease (GERD)/acid reflux

  • Ulcerative colitis

  • Crohn's disease

  • Previous gastric bypass

  • Small intestinal bacterial overgrowth (SIBO)


Form: Oral solution

Drug Website:

Manufacturer/Website: IBSA Group /

US Distributor/Website: IBSA Pharma Inc. /

Product Information and Inquiries: 800-587-3513 / /

Dosage Sizes: 13 mcg, 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg, 300 mcg 

Drug Insert:

tirosint colors.png

Excipients:  Glycerol, Water


Dyes: None 


Typical Retail Price: $145 - $175 (Note: Using the manufacturer copay card, or Tirosint® Direct program, patient cost is no more than $25-$40 per month.) 


Copay Tier: 3 or 4

Average Copay: $59 - $105

Manufacturer Copay Card: For patients with commercial health insurance and high copays, IBSA offers copay savings cards, which can be used at any retail pharmacy to save up to $105 off your Tirosint®-SOL prescription every month. According to the manufacturer, 9 out of 10 patients with insurance will pay as little as $25 for a month’s supply when using the card. For information, go to and to download a copay card, go to


Manufacturer Direct Purchase Program: Tirosint®-SOL manufacturer IBSA offers the Tirosint® Direct mail order program. You can pay $50 per month, or $120 for a three-month supply ($40 per month) – for Tirosint®-SOL. For information on how to participate in Tirosint® Direct, go to 

Patient Assistance Program: IBSA has a patient assistance program for Tirosint®-SOL, with eligibility based on your annual household income and prescription insurance status.  After you complete and return an enrollment form, if you qualify, you will automatically be mailed your first one- or three-month supply. You will then be eligible to receive free medicine for up to one year by calling to refill your prescription every month. You need to re-enroll each year to remain in the program. You can review the income eligibility requirements and apply for the program online at


To Report Adverse Events to IBSA: 800-587-3513 / /

To Report Adverse Events to FDA Medwatch: Call 800-FDA-1088, or visit the FDA Medwatch website at


The Levothyroxine Deep Dive program is copyright © 2020, Mary Shomon. All rights reserved.

Levoxyl®, Synthroid®, Tirosint®, Tirosint-SOL®, and Unithroid® are registered trademarks. Product images and logos used with permission. 


Mary Shomon does not provide medical advice, diagnosis or treatment.


The contents of this video and material contained on the website ("content") are for informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have learned from this video or site.

If you think you may have a medical emergency, call your doctor or 911 immediately. Mary Shomon does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned. Reliance on any information provided by Mary Shomon is solely at your own risk.

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